What is the main cause of non-Hodgkin's lymphoma?

Non-Hodgkin lymphoma is caused by a change (mutation) in the DNA of a type of white blood cell called lymphocytes, although the exact reason why this happens isn't known. DNA gives cells a basic set of instructions, such as when to grow and reproduce.

How do people get non-Hodgkin's lymphoma?

Gene changes related to NHL are usually acquired during life, rather than being inherited. Acquired gene changes can result from exposure to radiation, cancer-causing chemicals, or infections, but often these changes occur for no apparent reason.

Who is most likely to get non-Hodgkin's lymphoma?

More research is needed to understand the possible link between pesticides and the development of non-Hodgkin's lymphoma. Older age. Non-Hodgkin's lymphoma can occur at any age, but the risk increases with age. It's most common in people 60 or over.


What triggers lymphoma?

Causes of lymphoma

In most cases, there is no known cause for lymphoma. However, for a few types of lymphoma, scientists have identified a cause: Most cases of gastric MALT lymphoma are caused by a common bacterial infection called Helicobacter pylori. Usually, Helicobacter pylori causes stomach ulcers and indigestion.

Who is most likely to get Hodgkin lymphoma?

Age. People between the ages of 15 and 40 and people older than 55 are more likely to develop Hodgkin lymphoma. Gender. In general, men are slightly more likely to develop Hodgkin lymphoma than women, although the nodular sclerosis subtype is more common in women (see the Introduction).


Non-hodgkin lymphoma - causes, symptoms, diagnosis, treatment, pathology



Where does lymphoma usually start?

Lymphoma is cancer that begins in infection-fighting cells of the immune system, called lymphocytes. These cells are in the lymph nodes, spleen, thymus, bone marrow, and other parts of the body.

What virus causes Hodgkin's lymphoma?

Viruses: The Epstein-Barr virus, the same virus that causes infectious mononucleosis (mono), has been implicated as a cause of Hodgkin lymphoma. The presence of the genome of this virus is seen in 20%-80% of Hodgkin lymphoma tumors.

Can stress cause lymphoma?

For men, prolonged exposure to work-related stress has been linked to an increased likelihood of lung, colon, rectal, and stomach cancer and non-Hodgkin lymphoma.

How do you prevent non-Hodgkin's lymphoma?

There is no sure way to prevent non-Hodgkin lymphoma (NHL). Most people with NHL have no risk factors that can be changed, so there is no way to protect against these lymphomas.


What were your first signs of lymphoma?

Signs and symptoms of lymphoma may include:
  • Painless swelling of lymph nodes in your neck, armpits or groin.
  • Persistent fatigue.
  • Fever.
  • Night sweats.
  • Shortness of breath.
  • Unexplained weight loss.
  • Itchy skin.


How long can you have non-Hodgkin's lymphoma without knowing?

These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.

How did you know you had non-Hodgkin's lymphoma?

You can always ask questions about your imaging. Lymph node biopsy. Your doctor may recommend a lymph node biopsy procedure to remove all or part of a lymph node for laboratory testing. Analyzing lymph node tissue in a lab may reveal whether you have non-Hodgkin's lymphoma and, if so, which type.

Where does non-Hodgkin's lymphoma start?

Where does non-Hodgkin lymphoma occur in the body? Because the lymphatic system runs through your whole body, you can get NHL just about anywhere. NHL usually starts in the lymph nodes. It is quite common to find it in the neck, liver or spleen.


Which factors increase the likelihood of developing non-Hodgkin's lymphoma?

Non-Hodgkin Lymphoma Risk Factors
  • Age. Getting older is a strong risk factor for lymphoma overall, with most cases occurring in people in their 60s or older . ...
  • Gender. ...
  • Race, ethnicity, and geography. ...
  • Family History. ...
  • Exposure to certain chemicals and drugs. ...
  • Radiation exposure. ...
  • Having a weakened immune system. ...
  • Autoimmune diseases.


Which is worse non-Hodgkin's lymphoma or Hodgkin's lymphoma?

The prognosis of Hodgkin's lymphoma is also better than that of non-Hodgkin's lymphoma since non-Hodgkin's lymphoma is often diagnosed at a more advanced stage. Both forms of blood cancer are treatable when caught early, however.

Is non-Hodgkin's lymphoma a death sentence?

What is the survival rate for non-Hodgkin lymphoma? According to the American Cancer Society, about 71 percent of people of all races with non-Hodgkin lymphoma are still alive five years after diagnosis. Children tend to fare better, with 87 percent living for at least five years after diagnosis.

What part of the body does non-Hodgkin's lymphoma affect?

Non-Hodgkin lymphoma (NHL) is a cancer that affects the body's lymph system (also known as the lymphatic system). The lymph system is part of the immune system, which helps fight infections and some other diseases. It also helps fluids move through the body.


Is non-Hodgkin's lymphoma a terminal illness?

Yes, NHL is a very treatable disease and curable in many cases, particularly with aggressive NHL. Before treatment begins, it is necessary to know how far the cancer has advanced. This is called the stage of the disease. The stages begin with I (least severe) and go through IV (most severe).

Is anxiety a symptom of lymphoma?

Anxiety and fear are common among people with Hodgkin and non-Hodgkin lymphoma. In fact, anxiety and depression occur at a higher rate among people with blood cancers like lymphoma than in the general population.

Can lymphoma cause panic attacks?

Anxiety, depression, and even panic attacks may result from your reaction to the diagnosis of lymphoma, or from the effects of the disease or treatment.

Can lymphoma be reversed?

Overall, treatment for Hodgkin lymphoma is highly effective and most people with the condition are eventually cured.


What are the warning signs of Hodgkin's lymphoma?

Signs and symptoms of Hodgkin's lymphoma may include:
  • Painless swelling of lymph nodes in your neck, armpits or groin.
  • Persistent fatigue.
  • Fever.
  • Night sweats.
  • Losing weight without trying.
  • Severe itching.
  • Pain in your lymph nodes after drinking alcohol.


Does smoking cause Hodgkin's lymphoma?

Increased Hodgkin Lymphoma Risk Among Smokers

Overall, smokers tend to have a 40% higher risk of developing Hodgkin lymphoma. The risk was higher among current smokers (those who have been smoking within the last two years) than among those who have quit smoking.

Which type of lymphoma is worse?

The type of chemotherapy you receive will depend on how aggressive the cancer is. “T-cell non-Hodgkin lymphomas tend to be more aggressive,” Strati says. “Whereas B-cell non-Hodgkin lymphomas may be more slow-growing.”
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